The hair growth cycle as well as hair follicle growth and morphogenesis are coordinated
and complex processes that are dependent on the interaction of different signals and
stimuli developing within specialized cells of the epithelium and mesenchyme or stroma.
The hair follicle is a highly organized epithelial structure that is subject to cyclical
alterations following its development. The extended anagen phase is characterized
by massive cell proliferation and terminal differentiation and involves epithelial
growth of the hair follicle into the dermis with regeneration of the matrix, inner
root sheath, and formation of the hair shaft. The catagen phase is induced with rapid
involution of the hair follicle and proceeds to the telogen phase of follicular quiescence
that awaits the next signals for anagen.
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Article info
Footnotes
Address reprint requests to Mark R. Pittelkow, MD, Department of Dermatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905
Identification
Copyright
© 1996 W. B. Saunders Company. Published by Elsevier Inc. All rights reserved.
