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Botulinum Toxin for Axillary Hyperhidrosis

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      References

        • Doft M.A.
        • Kasten J.L.
        • Ascherman J.A.
        Treatment of axillary hyperhidrosis with botulinum toxin: a single surgeon’s experience with 53 consecutive patients.
        Aesthetic Plast Surg. 2011; 35: 1079-1086
        • Glaser D.A.
        • Hebert A.A.
        • Pariser D.M.
        • et al.
        Primary focal hyperhidrosis: scope of the problem.
        Cutis. 2007; 79: 5-17
        • Hornberger J.
        • Grimes K.
        • Naumann M.
        • et al.
        Recognition, diagnosis, and treatment of primary focal hyperhidrosis.
        J Am Acad Dermatol. 2004; 51: 274-286
        • Hamm H.
        • Naumann M.K.
        • Kowalski J.W.
        • et al.
        Primary focal hyperhidrosis: disease characteristics and functional impairment.
        Dermatology. 2006; 212: 343-353
        • Sato K.
        • Kang W.H.
        • Saga K.T.
        Biology of sweat glands and their disorders I. Normal sweat gland function.
        J Am Acad Dermatol. 1989; 20: 537-563
        • Kreyden O.
        • Scheidegger E.
        Anatomy of the sweat glands, pharmacology of botulinum toxin, and distinctive syndromes associated with hyperhidrosis.
        Clin Dermatol. 2004; 22: 40-44
        • Mota Juang J.
        • Sotto M.N.
        Anatomy and histology of sweat glands.
        in: Almeida A.R. Hexsel D.M. Hyperhidrosis and botulinum toxin. Edition of authors, São Paulo (Brazil)2004: 3-6
        • Bovell D.L.
        • Clunes M.T.
        • Elder H.Y.
        • et al.
        Ultrastructure of the hyperhidrotic eccrine sweat gland.
        Br J Dermatol. 2001; 145: 298-301
        • Bovell D.L.
        • MacDonald A.
        • Meyer B.A.
        • et al.
        The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis.
        Exp Dermatol. 2011; 20: 1017-1020
        • Lindsay S.L.
        • Holmes S.
        • Corbett A.D.
        • et al.
        Innervation and receptor profiles of the human apocrine (epitrichial) sweat gland: routes for intervention in bromhidrosis.
        Br J Dermatol. 2008; 159: 653-660
        • Atkins J.L.
        • Butler P.E.
        Hyperhidrosis: a review of current management.
        Plast Reconstr Surg. 2002; 110: 222-228
        • Sato K.
        • Kang W.T.
        • Saga K.T.
        Biology of sweat glands and their disorders II. Disorders of sweat gland function.
        J Am Acad Dermatol. 1989; 20: 713-726
        • Bovell D.
        • Corbett A.
        • Holmes S.
        • et al.
        The absence of apoeccrine glands in the human axilla has disease pathogenetic implications, including axillary hyperhidrosis.
        Br J Dermatol. 2007; 156: 1278-1286
        • Bechara F.
        Do we have apoeccrine sweat glands?.
        Int J Cosmet Sci. 2008; 30: 67-68
        • Kalner I.J.
        Same-patient prospective comparison of Botox versus Dysport for treatment of primary axillary hyperhidrosis and review of literature.
        J Drugs Dermatol. 2011; 10: 1013-1015
        • Trindade De Almeida A.R.
        • Secco L.C.
        • Carruthers A.
        Handling botulinum toxins: an updated literature review.
        Dermatol Surg. 2011; 37: 1553-1565
        • Rosell K.
        • Hymnelius K.
        • Swartling C.
        Botulinum toxin type A and B improve quality of life in patients with axillary and palmar hyperhidrosis.
        Acta Derm Venereol. 2013; 93: 335-339
        • Lowe N.J.
        • Glaser D.A.
        • Eadie N.
        • et al.
        Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety.
        J Am Acad Dermatol. 2007; 56: 604-611
        • Grunfeld A.
        • Murray C.A.
        • Solish N.
        Botulinum toxin for hyperhidrosis: a review.
        Am J Clin Dermatol. 2009; 10: 87-102
        • Heckmann M.
        • Ceballos-Baumann A.O.
        • Plewig G.
        Botulinum toxin A for axillary hyperhidrosis (excessive sweating).
        N Engl J Med. 2001; 344: 488-493
        • Naumann M.
        • Lowe N.J.
        Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial.
        BMJ. 2001; 323: 596-599
        • Scamoni S.
        • Valdatta L.
        • Frigo C.
        • et al.
        Treatment of primary axillary hyperhidrosis with botulinum toxin type A: our experience in 50 patients from 2007 to 2010.
        ISRN Dermatol. 2012; 2012: 702714
        • Lecouflet M.
        • Leux C.
        • Fenot M.
        • et al.
        Duration of efficacy increases with the repetition of botulinum toxin A injections in primary axillary hyperhidrosis: a study in 83 patients.
        J Am Acad Dermatol. 2013; 69: 960-964
        • Lakraj A.A.
        • Moghimi N.
        • Jabbari B.
        Hyperhidrosis: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins.
        Toxins (Basel). 2013; 5: 821-840
      1. Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm174949.htm. Accessed October 1, 2010.

        • Baumann L.
        • Slezinger A.
        • Halem M.
        • et al.
        Pilot study of the safety and efficacy of MyoblocTM (botulinum toxin type B) for treatment of axillary hyperhidrosis.
        Int J Dermatol. 2005; 44: 418-424
        • Nelson L.
        • Bachoo P.
        • Holmes J.
        Botulinum toxin type B: a new therapy for axillary hyperhidrosis.
        Br J Plast Surg. 2005; 58: 228-232
        • Dressler D.
        • Adib Saberi F.
        • Benecke R.
        Botulinum toxin type B for treatment of axillar hyperhidrosis.
        J Neurol. 2002; 249: 1729-1732
        • Frasson E.
        • Brigo F.
        • Acler M.
        • et al.
        Botulinum toxin type A vs type B for axillary hyperhidrosis in a case series of patients observed for 6 months.
        Arch Dermatol. 2011; 147: 122-123
        • Naumann M.
        • Dressler D.
        • Hallett M.
        • et al.
        Evidence-based review and assessment of botulinum neurotoxin for the treatment of secretory disorders.
        Toxicon. 2013; 67: 141-152
        • Talarico-Filho S.
        • Mendonça D.O.
        • Nascimento M.
        • et al.
        A double-blind, randomized, comparative study of two type A botulinum toxins in the treatment of primary axillary hyperhidrosis.
        Dermatol Surg. 2007; 33: 44-50
        • Dressler D.
        Comparing botox and xeomin for axillar hyperhidrosis.
        J Neural Transm. 2010; 117: 317-319
        • Gülec A.T.
        Dilution of botulinum toxin A in lidocaine vs. in normal saline for the treatment of primary axillary hyperhidrosis: a double-blind, randomized, comparative preliminary study.
        J Eur Acad Dermatol Venereol. 2012; 26: 314-318
        • Vadoud-Seyedi J.
        • Simonart T.
        Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study.
        Br J Dermatol. 2007; 156: 986-989
        • Goodman G.
        Diffusion and Short-term efficacy of Botulinum toxin A after addition of hyaluronidase and its possible application for the treatment of axillary hyperhidrosis.
        Dermatol Surg. 2003; 29: 533-538
        • Cohen J.L.
        • Cohen G.
        • Solish N.
        • et al.
        Diagnosis, impact, and management of focal hyperhidrosis: treatment review including botulinum toxin therapy.
        Facial Plast Surg Clin North Am. 2007; 15 (v–vi): 17-30
        • Glogau R.
        Hyperhidrosis and botulinum toxin A: patient selection and techniques.
        Clin Dermatol. 2004; 22: 45-52
        • Burks R.I.
        Povidone-iodine solution in wound treatment.
        Phys Ther. 1998; 78: 212-218
        • Bushara K.O.
        • Park D.M.
        Botulinum toxin and sweating.
        J Neurol Neurosurg Psychiatry. 1994; 54 ([letter]): 1437
        • Hund M.
        • Kinkelin I.
        • Naumann M.
        • et al.
        Definition of axillary hyperhidrosis by gravimetric assessment.
        Arch Dermatol. 2002; 138: 539-541
        • Bahmer F.
        • Sachse M.
        Hyperhidrosis area and severity index.
        Dermatol Surg. 2008; 34 ([letter]): 1744-1745
        • Odderson I.R.
        Long-term quantitative benefits of botulinum toxin A in the treatment of axillary hyperhidrosis.
        Dermatol Surg. 2002; 28: 480-483
        • Skiveren J.
        • Larsen H.N.
        • Kjaerby E.
        • et al.
        The influence of needle size on pain perception in patients treated with botulinum toxin A injections for axillary hyperhidrosis.
        Acta Derm Venereol. 2011; 91: 72-74
        • Klein A.W.
        Complication, adverse reaction, and insights with the use of botulinum toxin.
        Dermatol Surg. 2003; 29: 549-556
        • Grimalt R.
        • Moreno-Arias G.A.
        • Ferrando J.
        Multi-injection plate for botulinum toxin application in the treatment of axillary hyperhidrosis.
        Dermatol Surg. 2001; 27: 543-544
        • Jain S.
        A new multiple site marking grid for botulinum toxin application in the treatment of axillary hyperhidrosis.
        Br J Dermatol. 2006; 154: 375-391
        • Glogau R.G.
        Topically applied botulinum toxin type A for the treatment of primary axillary hyperhidrosis: results of a randomized, blinded, vehicle-controlled study.
        Dermatol Surg. 2007; 33: S76-S80
        • Chow A.
        • Wilder-Smith E.P.
        Effect of transdermal botulinum toxin on sweat secretion in subjects with idiopathic palmar hyperhidrosis.
        Br J Dermatol. 2009; 160: 721-723